| 1. Identity statement | |
| Reference Type | Journal Article |
| Site | plutao.sid.inpe.br |
| Holder Code | isadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S |
| Identifier | J8LNKAN8RW/3C64BRB |
| Repository | dpi.inpe.br/plutao/2012/06.21.22.18 (restricted access) |
| Last Update | 2012:09.03.18.09.43 (UTC) administrator |
| Metadata Repository | dpi.inpe.br/plutao/2012/06.21.22.18.20 |
| Metadata Last Update | 2018:06.05.00.01.51 (UTC) administrator |
| Secondary Key | INPE--PRE/ |
| DOI | 10.1002/em.21678 |
| ISSN | 0893-6692 |
| Label | lattes: 0549130828972280 5 SchuchYMYSAMM:2012:DNDaPr |
| Citation Key | SchuchYMYSAMM:2012:DNDaPr |
| Title | DNA damage profiles induced by sunlight at different latitudes  |
| Year | 2012 |
| Month | Abr. |
| Access Date | 2024, May 18 |
| Secondary Type | PRE PI |
| Number of Files | 1 |
| Size | 1292 KiB |
| 2. Context | |
| Author | 1 Schuch, André Passaglia 2 Yagura, Teiti 3 Makita, Kazuo 4 Yamamoto, Hiromasa 5 Schuch, Nelson Jorge 6 Agnez-Lima, Lucymara Fassarella 7 MacMahon, Ricardo Monreal 8 Menck, Carlos Frederico Martins |
| Resume Identifier | 1 2 3 4 5 8JMKD3MGP5W/3C9JHUD |
| Group | 1 2 3 4 5 CRS-CCR-INPE-MCTI-GOV-BR |
| Affiliation | 1 Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil 2 Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil 3 Faculty of Engineering, Takushoku University, Tokyo, Japan 4 Department of Physics, Rikkyo University, Tokyo, Japan 5 Instituto Nacional de Pesquisas Espaciais (INPE) 6 Department of Genetics and Cell Biology, Federal University of Rio Grande do Norte, Natal, RN, Brazil 7 Department of Mathematics and Physics, University of Magallanes Punta Arenas, Chile 8 Department of Mathematics and Physics, University of Magallanes, Punta Arenas, Chile |
| Author e-Mail Address | 1 2 3 4 5 njschuch@lacesm.ufsm.br |
| e-Mail Address | njschuch@lacesm.ufsm.br |
| Journal | Environmental and Molecular Mutagenesis |
| Volume | 53 |
| Number | 3 |
| Pages | 198-206 |
| Secondary Mark | B1_BIOTECNOLOGIA B1_CIÊNCIAS_BIOLÓGICAS_I B2_CIÊNCIAS_BIOLÓGICAS_III A2_ECOLOGIA_E_MEIO_AMBIENTE A2_ENGENHARIAS_II C_ENSINO_DE_CIÊNCIAS_E_MATEMATICA B1_FARMÁCIA A2_INTERDISCIPLINAR B1_MEDICINA_II B1_MEDICINA_III B1_QUÍMICA |
| History (UTC) | 2012-06-22 00:06:40 :: lattes -> banon :: 2012 2012-06-22 00:09:27 :: banon -> lattes :: 2012 2012-06-22 00:11:01 :: lattes -> secretaria.cpa@dir.inpe.br :: 2012 2012-09-03 18:09:56 :: secretaria.cpa@dir.inpe.br -> administrator :: 2012 2018-06-05 00:01:51 :: administrator -> marciana :: 2012 |
| 3. Content and structure | |
| Is the master or a copy? | is the master |
| Content Stage | completed |
| Transferable | 1 |
| Content Type | External Contribution |
| Version Type | publisher |
| Keywords | solar ultraviolet radiation DNA photoproducts biological dosimetry DNA-dosimeter |
| Abstract | Despite growing knowledge on the biological effects of ultraviolet (UV) radiation on human health and ecosystems, it is still difficult to predict the negative impacts of the increasing incidence of solar UV radiation in a scenario of global warming and climate changes. Hence, the development and application of DNA-based biological sensors to monitor the solar UV radiation under different environmental conditions is of increasing importance. With a mind to rendering a molecular view-point of the genotoxic impact of sunlight, field experiments were undertaken with a DNA-dosimeter system in parallel with physical photometry of solar UVB/UVA radiation, at various latitudes in South America. On applying biochemical and immunological approaches based on specific DNA-repair enzymes and antibodies, for evaluating sunlight-induced DNA damage profiles, it became clear that the genotoxic potential of sunlight does indeed vary according to latitude. Notwithstanding, while induction of oxidized DNA bases is directly dependent on an increase in latitude, the generation of 6-4PPs is inversely so, whereby the latter can be regarded as a biomolecular marker of UVB incidence. This molecular DNA lesion-pattern largely reflects the relative incidence of UVA and UVB energy at any specific latitude. Hereby is demonstrated the applicability of this DNA-based biosensor for additional, continuous field experiments, as a means of registering variations in the genotoxic impact of solar UV radiation. |
| Area | CEA |
| Arrangement | urlib.net > BDMCI > Fonds > Produção anterior à 2021 > CRCRS > DNA damage profiles... |
| doc Directory Content | access |
| source Directory Content | there are no files |
| agreement Directory Content | there are no files |
| 4. Conditions of access and use | |
| Language | en |
| User Group | administrator banon lattes secretaria.cpa@dir.inpe.br |
| Reader Group | administrator banon secretaria.cpa@dir.inpe.br |
| Visibility | shown |
| Archiving Policy | denypublisher denyfinaldraft |
| Read Permission | deny from all and allow from 150.163 |
| Update Permission | not transferred |
| 5. Allied materials | |
| Next Higher Units | 8JMKD3MGPCW/3EUFCFP |
| Dissemination | WEBSCI |
| Host Collection | dpi.inpe.br/plutao@80/2008/08.19.15.01 |
| 6. Notes | |
| Empty Fields | alternatejournal archivist callnumber copyholder copyright creatorhistory descriptionlevel format isbn lineage mark mirrorrepository nextedition notes orcid parameterlist parentrepositories previousedition previouslowerunit progress project rightsholder schedulinginformation secondarydate session shorttitle sponsor subject targetfile tertiarymark tertiarytype typeofwork url |
| 7. Description control | |
| e-Mail (login) | marciana |
| update | |